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Braff began his career in stage productions of William Shakespeare's Twelfth Night and Macbeth at New York City's Public Theater, and also appeared in Woody Allen's 1993 film Manhattan Murder Mystery.

Braff has played the role of protagonist John "J.D." Dorian on the sitcom Scrubs since the show's debut in 2001. In addition to directing several episodes of Scrubs, Braff wrote, directed, and starred in 2004's Garden State.

Braff recently starred in the romantic drama The Last Kiss, which opened on September 15, 2006. In 2007, Braff starred in the film The Ex, which he has described as a "silly comedy," and which was released on May 11, 2007 and also starred Amanda Peet, Charles Grodin and Jason Bateman.

(wikipedia.org)